Dr. Sibylle Maletz

Dr. Sibylle Maletz


Send mailTel. +41 58 765 5787

FX E24
Überlandstrasse 133
8600 Dübendorf

Tasks at the Ecotox Centre

  • Establishment and implementation of a new method for the extraction of sediment and suspended matter samples for examination in in vitro bioassays 
  • Supervision of various projects in the field of aquatic ecotoxicology with a focus on hormone-active substances

Areas of Expertise

  • Aquatic ecotoxicology
    • Cell cultures
    • Endocrine disrupters
    • In vitro und in vivo bioassays
    • Supervision of student projects
  • Human reproductive biology (IVF)


  • since 2022

    Scientist in aquatic ecotoxicology at the Ecotox Centre

  • 2015 - 2021

    Reproductive biologist at the IVF laboratory of the KWZ Heidelberg (Germany)

  • 2007 - 2015

    PhD at the Rheinisch-Westfälische Technische Hochschule (RWTH) in Aachen (Germany) at the Institute of Biology V (Environmental Research)

  • 2007 - 2015

    Research associate at RWTH Aachen University (head of the cell culture laboratory; co-establishment of the teaching and research area of ecosystem analysis; establishment of an in vitro bioassay battery for the detection of endocrine disruptors)

  • 2000 - 2007

    Studies of Biology, Geography and Political Science at the Ruprecht-Karls-University Heidelberg (Germany)


Kuckelkorn, R. Redelstein, T. Heide, J. Kunze, S. Maletz, P. Waldmann, et al. (2018). A hierarchical testing strategy for micropollutants in drinking water regarding their potential endocrine-disrupting effects-towards health-related indicator values. Environmental Science and Pollution Research Vol. 25 Issue 5 Pages 4051-4065.

Y. Kunz, E. Simon, N. Creusot, B. S. Jayasinghe, C. Kienle, S. Maletz, et al. (2017). Effect-based tools for monitoring estrogenic mixtures: Evaluation of five in vitro bioassays. Water Research Vol. 110 Pages 378-388.

Schulze-Sylvester, W. Heimann, S. Maletz, T. B. Seiler, M. Brinkmann, H. Zielke, et al. (2016). Are sediments a risk? An ecotoxicological assessment of sediments from a quarry pond of the Upper Rhine River. Journal of Soils and Sediments Vol. 16 Issue 3 Pages 1069-1080.

Maletz, M. Wollenweber, K. Kubiak, A. Muller, S. Schmitz, D. Maier, et al. (2015). Investigation of potential endocrine disrupting effects of mosquito larvicidal Bacillus thuringiensis israelensis (Bti) formulations. Science of the Total Environment Vol. 536 Pages 729-738.

Simon, S. X. Maletz, H. Hollert, A. Schaffer and H. M. Maes (2014). Effects of multiwalled carbon nanotubes and triclocarban on several eukaryotic cell lines: elucidating cytotoxicity, endocrine disruption, and reactive oxygen species generation. Nanoscale Research Letters Vol. 9.

M. Maes, S. X. Maletz, H. T. Ratte, J. Hollender and A. Schaeffer (2014). Uptake, Elimination, and Biotransformation of 17 alpha-Ethinylestradiol by the Freshwater Alga Desmodesmus subspicatus. Environmental Science & Technology Vol. 48 Issue 20 Pages 12354-12361.

Brinkmann, S. Maletz, M. Krauss, K. Bluhm, S. Schiwy, J. Kuckelkorn, et al. (2014). Heterocyclic Aromatic Hydrocarbons Show Estrogenic Activity upon Metabolization in a Recombinant Transactivation Assay. Environmental Science & Technology Vol. 48 Issue 10 Pages 5892-5901.

Maletz, T. Floehr, S. Beier, C. Klumper, A. Brouwer, P. Behnisch, et al. (2013). In vitro characterization of the effectiveness of enhanced sewage treatment processes to eliminate endocrine activity of hospital effluents. Water Research Vol. 47 Issue 4 Pages 1545-1557.

Grummt, J. Kuckelkorn, A. Bahlmann, C. Baumstark-Khan, W. Brack, T. Braunbeck, et al. (2013). Tox-Box: securing drops of life - an enhanced health-related approach for risk assessment of drinking water in Germany. Environmental Sciences Europe Vol. 25 Issue 1 Pages 27.

Heger, K. Bluhm, M. T. Agler, S. Maletz, A. Schaffer, T. B. Seiler, et al. (2012). Biotests for hazard assessment of biofuel fermentation. Energy & Environmental Science Vol. 5 Issue 12 Pages 9778-9788.

Hecker, H. Hollert, R. Cooper, A. M. Vinggaard, Y. Akahori, M. Murphy, et al. (2011). The OECD validation program of the H295R steroidogenesis assay: Phase 3. Final inter-laboratory validation study. Environmental Science and Pollution Research Vol. 18 Issue 3 Pages 503-515.

Wolz, M. Fleig, T. Schulze, S. Maletz, U. Lubcke-von Varel, G. Reifferscheid, et al. (2010). Impact of contaminants bound to suspended particulate matter in the context of flood events. Journal of Soils and Sediments 2010 Vol. 10 Issue 6 Pages 1174-1185.

Wolz, M. Engwall, S. Maletz, H. O. Takner, B. van Bavel, U. Kammann, et al. (2008). Changes in toxicity and Ah receptor agonist activity of suspended particulate matter during flood events at the rivers Neckar and Rhine - a mass balance approach using in vitro methods and chemical analysis. Environmental Science and Pollution Research Vol. 15 Issue 7 Pages 536-553.